In vivo experiments revealed that antibodies to neurofascin and complement can selectively target nodes of Ranvier, cause axonal injury, and trigger disease exacerbation in EAE. Mathey et al17 also showed that NF155specific antibodies crossreact with NF186transfected cells. The recognition of NF186 at the nodes of Ranvier by these antibodies may initiate axonal injury and accelerate disease progression.As expected, ratings for the NFL's Kickoff Weekend were massive. A record total of 108.4 million viewers tuned into the games, according to the league. Three games (the two on NBC, plus Packers49ers on Fox) exceeded 25 million average viewers to rank among the seven most watched TV shows since the Super Bowl..

McKnight remained on his right side as he was examined for several minutes. It appeared trainers were also checking his lower left leg before he was removed on a cart. He was wearing an oxygen mask as he walked gingerly on his own into the locker room while a trainer h